🛡️ 100% Authentic – Japan domestic version
🚚 Ships from Tokyo
✨ Delivery in 4-6 business days
Transino Medicated Brightening Clear Lotion 150ml is a quasi-drug certified toner for skin with melasma, persistent sun spots, freckles, and post-inflammatory hyperpigmentation that has not responded to standard brightening toners — using Tranexamic Acid as the primary medicated active to block melanin production at the prostaglandin signalling level, which is upstream of where most brightening ingredients intervene.
How it works: Prostaglandins are inflammatory signalling molecules that melanocytes respond to by producing melanin — UV exposure and inflammation both trigger this prostaglandin pathway. Tranexamic Acid blocks the prostaglandin step specifically, preventing the signal from reaching the melanocyte in the first place. This is different from ingredients like Arbutin, which inhibit tyrosinase (the enzyme that converts the melanin signal into pigment) — TXA acts one step earlier, which is why it is effective for hormonally driven melasma where the trigger is chronic rather than UV-specific.
Transino Lotion vs Melano CC Lotion for dark spots: Both are quasi-drug brightening toners. Melano CC Lotion uses 3-O-Ethyl Ascorbic Acid (penetrating Vitamin C) — effective for UV-triggered sun spots and post-acne marks. Transino uses Tranexamic Acid — more effective for melasma (hormonal pigmentation), deep or persistent spots, and skin where Vitamin C alone has not produced sufficient results. For simultaneous Vitamin C and TXA benefits, the two toners can be alternated in morning and evening routines.
Known in Japan as トランシーノ 薬用ブライトニングクリアローション 150ml.